Challenges and Trends in the Analysis of Chemical Contaminants, Residues and Adulterants in Dietary Supplements

Lukas Vaclavik

Eurofins Food Integrity & Innovation, Otley Road, Harrogate, North Yorkshire, HG3 1PY, UK,

The sales and consumption of dietary supplements have considerably increased over the past decade worldwide.  Both ingredients and finished products are supplied to an increasingly globalized marketplace.  Chemical safety and quality of these products have become an area of concern both to consumers and regulatory agencies.  The major risks associated with consumption of dietary supplements is the potential presence of pesticide residues, naturally formed contaminants, such as mycotoxins and plant toxins, heavy metals and other industrial pollutants, allergens, as well as various adulterants.  To control the chemical safety of dietary supplements, reliable and fit-for-purpose methods meeting strict performance requirements need to be used.  This presentation will provide an overview of challenges faced by contract and control laboratories in the arena of supplement chemical safety testing.  It will discuss modern analytical approaches and recent trends that allow addressing issues related to low target levels, the need for wide analyte and matrix scope, reliable identification of positive findings and high throughput of the analysis.